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Mechanically switching single-molecule fluorescence of GFP by unfolding and refolding

Green fluorescent protein (GFP) variants are widely used as genetically encoded fluorescent fusion tags, and there is an increasing interest in engineering their structure to develop in vivo optical sensors, such as for optogenetics and force transduction. Ensemble experiments have shown that the fl...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ganim, Ziad, Rief, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651744/
https://ncbi.nlm.nih.gov/pubmed/29073015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704937114
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