Improved Prefusion Stability, Optimized Codon Usage, and Augmented Virion Packaging Enhance the Immunogenicity of Respiratory Syncytial Virus Fusion Protein in a Vectored-Vaccine Candidate

Respiratory syncytial virus (RSV) is the most important viral agent of severe pediatric respiratory tract disease worldwide, but it lacks a licensed vaccine or suitable antiviral drug. A live attenuated chimeric bovine/human parainfluenza virus type 3 (rB/HPIV3) was developed previously as a vector...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Liang, Bo, Ngwuta, Joan O., Surman, Sonja, Kabatova, Barbora, Liu, Xiang, Lingemann, Matthias, Liu, Xueqiao, Yang, Lijuan, Herbert, Richard, Swerczek, Joanna, Chen, Man, Moin, Syed M., Kumar, Azad, McLellan, Jason S., Kwong, Peter D., Graham, Barney S., Collins, Peter L., Munir, Shirin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651718/
https://ncbi.nlm.nih.gov/pubmed/28539444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00189-17
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