Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

In contrast to the negligible expression of the immunomodulating protein CD70 in normal tissue, we have demonstrated constitutive overexpression of CD70 on tumor cells in a subset of primary non-small cell lung cancer (NSCLC) biopsies. This can be exploited by CD70-targeting antibody-dependent cellu...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Jacobs, Julie, Deschoolmeester, Vanessa, Rolfo, Christian, Zwaenepoel, Karen, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, de Haard, Hans, Hermans, Christophe, Rottey, Sylvie, Vangestel, Christel, Lardon, Filip, Smits, Evelien, Pauwels, Patrick
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650323/
https://ncbi.nlm.nih.gov/pubmed/29088768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18202
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