Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy

In contrast to the negligible expression of the immunomodulating protein CD70 in normal tissue, we have demonstrated constitutive overexpression of CD70 on tumor cells in a subset of primary non-small cell lung cancer (NSCLC) biopsies. This can be exploited by CD70-targeting antibody-dependent cellu...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Jacobs, Julie, Deschoolmeester, Vanessa, Rolfo, Christian, Zwaenepoel, Karen, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, de Haard, Hans, Hermans, Christophe, Rottey, Sylvie, Vangestel, Christel, Lardon, Filip, Smits, Evelien, Pauwels, Patrick
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650323/
https://ncbi.nlm.nih.gov/pubmed/29088768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18202
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