Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

Although normally restricted to activated T and B cells and mature dendritic cells, constitutive expression of CD70, a member of the tumor necrosis family, has been described in both hematological and solid tumors, where it increases tumor cell and regulatory T cell survival by signaling through its...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Jacobs, Julie, Zwaenepoel, Karen, Rolfo, Christian, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, Hermans, Christophe, Smits, Evelien, Van Schil, Paul, Lardon, Filip, Deschoolmeester, Vanessa, Pauwels, Patrick
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537027/
https://ncbi.nlm.nih.gov/pubmed/25951351
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