Wird geladen...
High-Throughput Screening of HECT E3 Ubiquitin Ligases Using UbFluor
HECT E3 ubiquitin ligases are responsible for many human disease phenotypes, and are promising drug targets. However, screening assays for HECT E3 inhibitors are inherently complex, requiring upstream E1 and E2 enzymes as well as ubiquitin, ATP, and detection reagents. Intermediate ubiquitin thioest...
Gespeichert in:
| Veröffentlicht in: | Curr Protoc Chem Biol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650195/ https://ncbi.nlm.nih.gov/pubmed/28910856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpch.24 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|