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Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

In the last two decades, monoclonal antibodies have revolutionized the therapy of cancer patients. Although antibody therapy has continuously been improved, still a significant number of patients do not benefit from antibody therapy. Therefore, rational optimization of the antibody molecule by Fc en...

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發表在:Transfus Med Hemother
Main Authors: Kellner, Christian, Otte, Anna, Cappuzzello, Elisa, Klausz, Katja, Peipp, Matthias
格式: Artigo
語言:Inglês
出版: S. Karger GmbH 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649276/
https://ncbi.nlm.nih.gov/pubmed/29070978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000479980
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