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Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

In the last two decades, monoclonal antibodies have revolutionized the therapy of cancer patients. Although antibody therapy has continuously been improved, still a significant number of patients do not benefit from antibody therapy. Therefore, rational optimization of the antibody molecule by Fc en...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transfus Med Hemother
Prif Awduron: Kellner, Christian, Otte, Anna, Cappuzzello, Elisa, Klausz, Katja, Peipp, Matthias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger GmbH 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649276/
https://ncbi.nlm.nih.gov/pubmed/29070978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000479980
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