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Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

In the last two decades, monoclonal antibodies have revolutionized the therapy of cancer patients. Although antibody therapy has continuously been improved, still a significant number of patients do not benefit from antibody therapy. Therefore, rational optimization of the antibody molecule by Fc en...

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Publicat a:Transfus Med Hemother
Autors principals: Kellner, Christian, Otte, Anna, Cappuzzello, Elisa, Klausz, Katja, Peipp, Matthias
Format: Artigo
Idioma:Inglês
Publicat: S. Karger GmbH 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649276/
https://ncbi.nlm.nih.gov/pubmed/29070978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000479980
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