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Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

In the last two decades, monoclonal antibodies have revolutionized the therapy of cancer patients. Although antibody therapy has continuously been improved, still a significant number of patients do not benefit from antibody therapy. Therefore, rational optimization of the antibody molecule by Fc en...

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Foilsithe in:Transfus Med Hemother
Main Authors: Kellner, Christian, Otte, Anna, Cappuzzello, Elisa, Klausz, Katja, Peipp, Matthias
Formáid: Artigo
Teanga:Inglês
Foilsithe: S. Karger GmbH 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649276/
https://ncbi.nlm.nih.gov/pubmed/29070978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000479980
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