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Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

In the last two decades, monoclonal antibodies have revolutionized the therapy of cancer patients. Although antibody therapy has continuously been improved, still a significant number of patients do not benefit from antibody therapy. Therefore, rational optimization of the antibody molecule by Fc en...

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Bibliografiske detaljer
Udgivet i:Transfus Med Hemother
Main Authors: Kellner, Christian, Otte, Anna, Cappuzzello, Elisa, Klausz, Katja, Peipp, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger GmbH 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649276/
https://ncbi.nlm.nih.gov/pubmed/29070978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000479980
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