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Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer

Oncogenic mutations, such as Ras mutations, drive not only enhanced proliferation but also the metabolic adaptations that confer to cancer cells the ability to sustain cell growth in a harsh tumor microenvironment. These adaptations might represent metabolic vulnerabilities that can be exploited to...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Recouvreux, Maria Victoria, Commisso, Cosimo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649207/
https://ncbi.nlm.nih.gov/pubmed/29085336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00261
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