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Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer

Oncogenic mutations, such as Ras mutations, drive not only enhanced proliferation but also the metabolic adaptations that confer to cancer cells the ability to sustain cell growth in a harsh tumor microenvironment. These adaptations might represent metabolic vulnerabilities that can be exploited to...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Recouvreux, Maria Victoria, Commisso, Cosimo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649207/
https://ncbi.nlm.nih.gov/pubmed/29085336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00261
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