Effect of Semaglutide on the Pharmacokinetics of Metformin, Warfarin, Atorvastatin and Digoxin in Healthy Subjects

BACKGROUND AND OBJECTIVE: Semaglutide is a glucagon-like peptide-1 analogue in development for the once-weekly treatment of type 2 diabetes mellitus. Its effect on the rate and extent of absorption of concomitant oral medications (metformin, warfarin, atorvastatin and digoxin) was evaluated in healt...

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Опубликовано в: :Clin Pharmacokinet
Главные авторы: Hausner, Helene, Derving Karsbøl, Julie, Holst, Anders G., Jacobsen, Jacob B., Wagner, Frank-Dietrich, Golor, Georg, Anderson, Thomas W.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2017
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Original Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648738/
https://ncbi.nlm.nih.gov/pubmed/28349387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0532-6
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