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Effect of Oral Semaglutide on the Pharmacokinetics of Lisinopril, Warfarin, Digoxin, and Metformin in Healthy Subjects

BACKGROUND: Oral semaglutide is a tablet co-formulation of the human glucagon-like peptide-1 (GLP-1) analog semaglutide with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). The absorption of coadministered oral drugs may be altered due to enhancement by SNAC, potentia...

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Foilsithe in:Clin Pharmacokinet
Main Authors: Bækdal, Tine A., Borregaard, Jeanett, Hansen, Cilie W., Thomsen, Mette, Anderson, Thomas W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer International Publishing 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719321/
https://ncbi.nlm.nih.gov/pubmed/30945118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00756-2
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