Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects with Renal Impairment

BACKGROUND: Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been co-formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) as a tablet for oral administration. This trial (NCT02014259) investigated the pharmacokinetics, safety and tolerability of...

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Bibliographic Details
Published in:Clin Pharmacokinet
Main Authors: Granhall, Charlotte, Søndergaard, Flemming L., Thomsen, Mette, Anderson, Thomas W.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2018
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Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267549/
https://ncbi.nlm.nih.gov/pubmed/29623579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0649-2
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