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Interpreting reverse transcriptase termination and mutation events for greater insight into the chemical probing of RNA

Chemical probing has the power to provide insight into RNA conformation in vivo and in vitro, but interpreting the results depends on methods to detect the chemically modified nucleotides. Traditionally, the presence of modified bases was inferred from their ability to halt reverse transcriptase dur...

詳細記述

保存先:
書誌詳細
出版年:Biochemistry
主要な著者: Sexton, Alec N., Wang, Peter Y., Rutenberg-Schoenberg, Michael, Simon, Matthew D.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648349/
https://ncbi.nlm.nih.gov/pubmed/28820243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00323
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