Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma

Maintenance of telomere length is a critical hallmark of malignant transformation. While silenced in somatic cells, telomerase reverse transcriptase (TERT), the catalytic subunit of telomerase, is frequently overexpressed in malignant cells thereby maintaining their telomere length. Specific point m...

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: LINDNER, SVEN, BACHMANN, HAGEN S., ODERSKY, ANDREA, SCHAEFERS, SIMON, KLEIN-HITPASS, LUDGER, HERO, BARBARA, FISCHER, MATTHIAS, EGGERT, ANGELIKA, SCHRAMM, ALEXANDER, SCHULTE, JOHANNES H.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486810/
https://ncbi.nlm.nih.gov/pubmed/26171145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2015.463
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