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Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma
Maintenance of telomere length is a critical hallmark of malignant transformation. While silenced in somatic cells, telomerase reverse transcriptase (TERT), the catalytic subunit of telomerase, is frequently overexpressed in malignant cells thereby maintaining their telomere length. Specific point m...
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| Gepubliceerd in: | Biomed Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
D.A. Spandidos
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486810/ https://ncbi.nlm.nih.gov/pubmed/26171145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2015.463 |
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