Mutations in the C-terminal region of the HIV-1 reverse transcriptase and their correlation with drug resistance associated mutations and antiviral treatment

OBJECTIVE: Replication of HIV-1 after cell entry is essentially dependent on the reverse transcriptase (RT). Antiretroviral drugs impairing the function of the RT currently aim at the polymerase subunit. One reason for failure of antiretroviral treatment is the evolvement of resistance-associated mu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Michels, I, Staszewski, S, Gürtler, L, Nisius, G, Müller, A, Locher, L, Doerr, H-W, Stürmer, M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352185/
https://ncbi.nlm.nih.gov/pubmed/21156400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-15-10-415
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados