Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

Chromatin structure is tightly intertwined with transcription regulation. Here we compared the chromosomal architectures of fetal and adult human erythroblasts and found that, globally, chromatin structures and compartments A/B are highly similar at both developmental stages. At a finer scale, we de...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Huang, Peng, Keller, Cheryl A., Giardine, Belinda, Grevet, Jeremy D., Davies, James O.J., Hughes, Jim R., Kurita, Ryo, Nakamura, Yukio, Hardison, Ross C., Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647940/
https://ncbi.nlm.nih.gov/pubmed/28916711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303461.117
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