Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element

Chromatin structure is tightly intertwined with transcription regulation. Here we compared the chromosomal architectures of fetal and adult human erythroblasts and found that, globally, chromatin structures and compartments A/B are highly similar at both developmental stages. At a finer scale, we de...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Huang, Peng, Keller, Cheryl A., Giardine, Belinda, Grevet, Jeremy D., Davies, James O.J., Hughes, Jim R., Kurita, Ryo, Nakamura, Yukio, Hardison, Ross C., Blobel, Gerd A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647940/
https://ncbi.nlm.nih.gov/pubmed/28916711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303461.117
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