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OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs
Ectopic expression of lineage master regulators induces transdifferentiation. Whether cell fate transitions can be induced during various developmental stages has not been systemically examined. Here we discover that amongst different developmental stages, mouse embryonic stem cells (mESCs) are resi...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647326/ https://ncbi.nlm.nih.gov/pubmed/29044103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01122-1 |
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