OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs

Ectopic expression of lineage master regulators induces transdifferentiation. Whether cell fate transitions can be induced during various developmental stages has not been systemically examined. Here we discover that amongst different developmental stages, mouse embryonic stem cells (mESCs) are resi...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Sheinboim, Danna, Maza, Itay, Dror, Iris, Parikh, Shivang, Krupalnik, Vladislav, Bell, Rachel E., Zviran, Asaf, Suita, Yusuke, Hakim, Ofir, Mandel-Gutfreund, Yael, Khaled, Mehdi, Hanna, Jacob H., Levy, Carmit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647326/
https://ncbi.nlm.nih.gov/pubmed/29044103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01122-1
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