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Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage
Melanoma incidence continues to rise at an alarming rate while effective systemic therapies remain very limited. Microphthalmia-associated transcription factor (MITF) is required for development of melanocytes and is an amplified oncogene in a fraction of human melanomas. MITF also plays an oncogeni...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3771662/ https://ncbi.nlm.nih.gov/pubmed/18627530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00480.x |
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