Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage

Melanoma incidence continues to rise at an alarming rate while effective systemic therapies remain very limited. Microphthalmia-associated transcription factor (MITF) is required for development of melanocytes and is an amplified oncogene in a fraction of human melanomas. MITF also plays an oncogeni...

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Bibliographic Details
Main Authors:	Yokoyama, Satoru, Feige, Erez, Poling, Laura L., Levy, Carmit, Widlund, Hans R., Khaled, Mehdi, Kung, Andrew L., Fisher, David E.
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3771662/ https://ncbi.nlm.nih.gov/pubmed/18627530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00480.x
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Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage

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