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Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling

Previous studies have demonstrated that lercanidipine, a calcium channel blocker, may protect against cardiac hypertrophy; however, the underlying mechanisms remain unclear. In the present study, the effects of lercanidipine on hypertrophy and the mechanisms involved were investigated. Cardiomyocyte...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Chen, Yuezhang, Yuan, Jie, Jiang, Guoliang, Zhu, Jianbing, Zou, Yunzeng, Lv, Qianzhou
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646991/
https://ncbi.nlm.nih.gov/pubmed/28849081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7211
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