The sequence preference of DNA methylation variation in mammalians

Methylation of cytosine at the 5 position of the pyrimidine ring is the most prevalent and significant epigenetic modifications in mammalian DNA. The CpG methylation level shows a bimodal distribution but the bimodality can be overestimated due to the heterogeneity of per-base depth. Here, we develo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zhang, Ling, Gu, Chan, Yang, Lijiang, Tang, Fuchou, Gao, Yi Qin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646869/
https://ncbi.nlm.nih.gov/pubmed/29045493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186559
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