Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information

Transcription factors play key roles in cell-fate decisions by regulating 3D genome conformation and gene expression. The traditional view is that methylation of DNA hinders transcription factors binding to them, but recent research has shown that many transcription factors prefer to bind to methyla...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Liu, Meng-Lu, Su, Wei, Wang, Jia-Shu, Yang, Yu-He, Yang, Hui, Lin, Hao
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691157/
https://ncbi.nlm.nih.gov/pubmed/33294291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.07.035
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