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Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information

Transcription factors play key roles in cell-fate decisions by regulating 3D genome conformation and gene expression. The traditional view is that methylation of DNA hinders transcription factors binding to them, but recent research has shown that many transcription factors prefer to bind to methyla...

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Liu, Meng-Lu, Su, Wei, Wang, Jia-Shu, Yang, Yu-He, Yang, Hui, Lin, Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691157/
https://ncbi.nlm.nih.gov/pubmed/33294291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.07.035
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