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DNA Sequence Explains Seemingly Disordered Methylation Levels in Partially Methylated Domains of Mammalian Genomes

For the most part metazoan genomes are highly methylated and harbor only small regions with low or absent methylation. In contrast, partially methylated domains (PMDs), recently discovered in a variety of cell lines and tissues, do not fit this paradigm as they show partial methylation for large por...

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Detalhes bibliográficos
Main Authors: Gaidatzis, Dimos, Burger, Lukas, Murr, Rabih, Lerch, Anita, Dessus-Babus, Sophie, Schübeler, Dirk, Stadler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923675/
https://ncbi.nlm.nih.gov/pubmed/24550741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004143
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