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DNA Sequence Explains Seemingly Disordered Methylation Levels in Partially Methylated Domains of Mammalian Genomes

For the most part metazoan genomes are highly methylated and harbor only small regions with low or absent methylation. In contrast, partially methylated domains (PMDs), recently discovered in a variety of cell lines and tissues, do not fit this paradigm as they show partial methylation for large por...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gaidatzis, Dimos, Burger, Lukas, Murr, Rabih, Lerch, Anita, Dessus-Babus, Sophie, Schübeler, Dirk, Stadler, Michael B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923675/
https://ncbi.nlm.nih.gov/pubmed/24550741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004143
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