Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D(3) metabolism

RATIONALE: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Mulligan, Jennifer K., Pasquini, Whitney N., Carroll, William W., Williamson, Tucker, Reaves, Nicholas, Patel, Kunal J., Mappus, Elliott, Schlosser, Rodney J., Atkinson, Carl
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646812/
https://ncbi.nlm.nih.gov/pubmed/29045457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186374
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