Vitamin D deficiency is associated with increased human sinonasal fibroblast proliferation in chronic rhinosinusitis with nasal polyps

BACKGROUND: Vitamin D3 (VD3) is a steroid hormone with known anti-proliferative properties. Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be VD3 deficient. Moreover, VD3 deficiency is associated with worse disease in patients with CRSwNP. One cell type thought to...

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Pubblicato in:Int Forum Allergy Rhinol
Autori principali: Carroll, William W., Schlosser, Rodney J., O’Connell, Brendan P., Soler, Zachary M., Mulligan, Jennifer K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921271/
https://ncbi.nlm.nih.gov/pubmed/26750566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.21704
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