Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D(3) metabolism

RATIONALE: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency...

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Publicado en:PLoS One
Autores principales: Mulligan, Jennifer K., Pasquini, Whitney N., Carroll, William W., Williamson, Tucker, Reaves, Nicholas, Patel, Kunal J., Mappus, Elliott, Schlosser, Rodney J., Atkinson, Carl
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646812/
https://ncbi.nlm.nih.gov/pubmed/29045457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186374
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