Dietary vitamin D3 deficiency exacerbates sinonasal inflammation and alters local 25(OH)D(3) metabolism

RATIONALE: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) have been shown to be vitamin D3 (VD3) deficient, which is associated with more severe disease and increased polyp size. To gain mechanistic insights into these observational studies, we examined the impact of VD3 deficiency...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mulligan, Jennifer K., Pasquini, Whitney N., Carroll, William W., Williamson, Tucker, Reaves, Nicholas, Patel, Kunal J., Mappus, Elliott, Schlosser, Rodney J., Atkinson, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646812/
https://ncbi.nlm.nih.gov/pubmed/29045457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186374
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