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Tandem trimer pyrrole–imidazole polyamide probes targeting 18 base pairs in human telomere sequences
The binding of molecules to specific DNA sequences is important for imaging genome DNA and for studying gene expression. Increasing the number of base pairs targeted by these molecules would provide greater specificity. N-Methylpyrrole–N-methylimidazole (Py–Im) polyamides are one type of such molecu...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5645774/ https://ncbi.nlm.nih.gov/pubmed/29308145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03755c |
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