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Tandem trimer pyrrole–imidazole polyamide probes targeting 18 base pairs in human telomere sequences

The binding of molecules to specific DNA sequences is important for imaging genome DNA and for studying gene expression. Increasing the number of base pairs targeted by these molecules would provide greater specificity. N-Methylpyrrole–N-methylimidazole (Py–Im) polyamides are one type of such molecu...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Kawamoto, Yusuke, Sasaki, Asuka, Hashiya, Kaori, Ide, Satoru, Bando, Toshikazu, Maeshima, Kazuhiro, Sugiyama, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645774/
https://ncbi.nlm.nih.gov/pubmed/29308145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc03755c
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