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Specific targeting of insect and vertebrate telomeres with pyrrole and imidazole polyamides
DNA minor groove-binding compounds (polyamides) that target insect and vertebrate telomeric repeats with high specificity were synthesized. Base pair recognition of these polyamides is based on the presence of the heterocyclic amino acids pyrrole and imidazole. One compound (TH52B) interacts uniquel...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150199/ https://ncbi.nlm.nih.gov/pubmed/11406598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.12.3218 |
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