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Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers

Telomeres are nucleoprotein structures that cap the ends of linear chromosomes. Telomeric DNA comprises terminal tracts of G-rich tandem repeats, which are inherently difficult for the replication machinery to navigate. Structural aberrations that promote activation of the alternative lengthening of...

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Autori principali: Robert Lu, Hilda A. Pickett
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2022-03-01
Serie:Open Biology
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Accesso online:https://royalsocietypublishing.org/doi/10.1098/rsob.220011
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