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Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants
N-methylpyrrole (Py)-N-methylimidazole (Im) polyamides are small organic molecules that bind to DNA with sequence specificity and can be used as synthetic DNA-binding ligands. In this study, five hairpin eight-ring Py–Im polyamides 1–5 with different number of Im rings were synthesized, and their bi...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526260/ https://ncbi.nlm.nih.gov/pubmed/23042247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks897 |
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