LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8(+) T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection

Integrins mediate the lymphocyte migration into an infected tissue, and these cells are essential for controlling the multiplication of many intracellular parasites such as Trypanosoma cruzi, the causative agent of Chagas disease. Here, we explore LFA-1 and VLA-4 roles in the migration of specific C...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ferreira, Camila Pontes, Cariste, Leonardo Moro, Santos Virgílio, Fernando Dos, Moraschi, Barbara Ferri, Monteiro, Caroline Brandão, Vieira Machado, Alexandre M., Gazzinelli, Ricardo Tostes, Bruna-Romero, Oscar, Menin Ruiz, Pedro Luiz, Ribeiro, Daniel Araki, Lannes-Vieira, Joseli, Lopes, Marcela de Freitas, Rodrigues, Mauricio Martins, de Vasconcelos, José Ronnie Carvalho
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645645/
https://ncbi.nlm.nih.gov/pubmed/29081775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01291
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