Rapamycin Improves the Response of Effector and Memory CD8(+) T Cells Induced by Immunization With ASP2 of Trypanosoma cruzi

Deficiency in memory formation and increased immunosenescence are pivotal features of Trypanosoma cruzi infection proposed to play a role in parasite persistence and disease development. The vaccination protocol that consists in a prime with plasmid DNA followed by the boost with a deficient recombi...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Moraschi, Barbara Ferri, Noronha, Isaú Henrique, Ferreira, Camila Pontes, Cariste, Leonardo M., Monteiro, Caroline B., Denapoli, Priscila, Vrechi, Talita, Pereira, Gustavo J. S., Gazzinelli, Ricardo T., Lannes-Vieira, Joseli, Rodrigues, Maurício M., Bortoluci, Karina R., Vasconcelos, José Ronnie C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cellular and Infection Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191465/
https://ncbi.nlm.nih.gov/pubmed/34123875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.676183
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