Simultaneous Quantification of Free Cholesterol, Cholesteryl Esters, and Triglycerides without Ester Hydrolysis by UHPLC Separation and In-Source Collision Induced Dissociation Coupled MS/MS

We demonstrate the application of in-source nitrogen collision-induced dissociation (CID) that eliminates the need for ester hydrolysis before simultaneous analysis of esterified cholesterol (EC) and triglycerides (TG) along with free cholesterol (FC) from human serum, using normal phase liquid chro...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Gardner, Michael S., McWilliams, Lisa G., Jones, Jeffrey I., Kuklenyik, Zsuzsanna, Pirkle, James L., Barr, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645443/
https://ncbi.nlm.nih.gov/pubmed/28801822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1756-2
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