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Human microglia and astrocytes express cGAS-STING viral sensing components

While microglia and astrocytes are known to produce key inflammatory and anti-viral mediators following infection with replicative DNA viruses, the mechanisms by which these cell types perceive such threats are poorly understood. Recently, cyclic GMP-AMP synthase (cGAS) has been identified as an imp...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Jeffries, Austin M., Marriott, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645252/
https://ncbi.nlm.nih.gov/pubmed/28830822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2017.08.039
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