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THE RAC GTPase IN CANCER: FROM OLD CONCEPTS TO NEW PARADIGMS

Rho family GTPases are critical regulators of cellular functions that play important roles in cancer progression. Aberrant activity of Rho small G-proteins, particularly Rac1 and their regulators, is a hallmark of cancer, and contributes to the tumorigenic and metastatic phenotypes of cancer cells....

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Kazanietz, Marcelo G., Caloca, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645227/
https://ncbi.nlm.nih.gov/pubmed/28807941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1456
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