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THE RAC GTPase IN CANCER: FROM OLD CONCEPTS TO NEW PARADIGMS

Rho family GTPases are critical regulators of cellular functions that play important roles in cancer progression. Aberrant activity of Rho small G-proteins, particularly Rac1 and their regulators, is a hallmark of cancer, and contributes to the tumorigenic and metastatic phenotypes of cancer cells....

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Publicado en:Cancer Res
Autores principales: Kazanietz, Marcelo G., Caloca, Maria J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645227/
https://ncbi.nlm.nih.gov/pubmed/28807941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1456
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