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Rare Streptomyces N-Formyl Amino-salicylamides Inhibit Oncogenic K-Ras
During a search for inhibitors of oncogenic K-Ras, we detected two known and two new examples of the rare neoantimycin structure class from a liquid cultivation of Streptomyces orinoci, and reassigned/assigned structures to all based on detailed spectroscopic analysis and microscale C(3) Marfey’s an...
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| Publicado en: | Org Lett |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5645021/ https://ncbi.nlm.nih.gov/pubmed/25238489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502376e |
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