Llwytho...

Rare Streptomyces N-Formyl Amino-salicylamides Inhibit Oncogenic K-Ras

During a search for inhibitors of oncogenic K-Ras, we detected two known and two new examples of the rare neoantimycin structure class from a liquid cultivation of Streptomyces orinoci, and reassigned/assigned structures to all based on detailed spectroscopic analysis and microscale C(3) Marfey’s an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Org Lett
Prif Awduron: Salim, Angela A., Cho, Kwang-Jin, Tan, Lingxiao, Quezada, Michelle, Lacey, Ernest, Hancock, John F., Capon, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645021/
https://ncbi.nlm.nih.gov/pubmed/25238489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502376e
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