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Approaches to inhibiting oncogenic K-Ras
Activating somatic K-Ras mutations are associated with >15% all human tumors and up to 90% of specific tumor types such as pancreatic cancer. Successfully inhibiting abnormal K-Ras signaling would therefore be a game changer in cancer therapy. However, K-Ras has long been considered an undruggabl...
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| Publicado no: | Small GTPases |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849769/ https://ncbi.nlm.nih.gov/pubmed/31438765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2019.1655883 |
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