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Oligomycins as inhibitors of K-Ras plasma membrane localisation
Frequently present in pancreatic, colorectal and non-small cell lung carcinomas, oncogenic mutant K-Ras must be localised to the plasma membrane (PM) to be functional. Inhibitors of K-Ras PM localisation are therefore putative cancer chemotherapeutics. By screening a microbial extract library in a h...
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| Publicat a: | Org Biomol Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689619/ https://ncbi.nlm.nih.gov/pubmed/26565618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02020d |
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