Understanding Curli Amyloid-Protein Aggregation by Hydrogen–Deuterium Exchange and Mass Spectrometry

Bacteria within Curli biofilms are protected from environmental pressures (e.g., disinfectants, antibiotics), and this is responsible for intractable infections. Understanding aggregation of the major protein component of Curli, CsgA, may uncover disease-associated amyloidogenesis mechanisms. Here,...

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Bibliographic Details
Published in:Int J Mass Spectrom
Main Authors: Wang, Hanliu, Shu, Qin, Rempel, Don L., Frieden, Carl, Gross, Michael L.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644351/
https://ncbi.nlm.nih.gov/pubmed/29056864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2016.10.006
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