Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure

BACKGROUND: Accurate inference of genetic ancestry is of fundamental interest to many biomedical, forensic, and anthropological research areas. Genetic ancestry memberships may relate to genetic disease risks. In a genome association study, failing to account for differences in genetic ancestry betw...

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Foilsithe in:BMC Genomics
Main Authors: Byun, Jinyoung, Han, Younghun, Gorlov, Ivan P., Busam, Jonathan A., Seldin, Michael F., Amos, Christopher I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Methodology Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644186/
https://ncbi.nlm.nih.gov/pubmed/29037167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4166-8
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