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Accounting for ancestry: population substructure and genome-wide association studies

Accounting for the genetic substructure of human populations has become a major practical issue for studying complex genetic disorders. Allele frequency differences among ethnic groups and subgroups and admixture between different ethnic groups can result in frequent false-positive results or reduce...

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Detalhes bibliográficos
Main Authors: Tian, Chao, Gregersen, Peter K., Seldin, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782357/
https://ncbi.nlm.nih.gov/pubmed/18852203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn268
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